By Gordon Guyatt, Drummond Rennie, Maureen O. Meade, Deborah J. Cook
The prime advisor to the rules and medical functions of evidence-based medication.
Read Online or Download A Manual for Evidence-Based Clinical Practice (3rd Edition) (Users' Guides to the Medical Literature) PDF
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Extra info for A Manual for Evidence-Based Clinical Practice (3rd Edition) (Users' Guides to the Medical Literature)
Indd 3 16102014 10:50:40 4 The Foundations The objective of this book is to help you make effi cient use of the published literature in guiding your patient care. What does the published literature comprise? Our definition is broad. You may find evidencea in a wide variety of sources, including origi nal journal articles, reviews and synopses of primary studies, clinical practice guidelines, and traditional and innovative medical textbooks. Increasingly, cli nicians can most easily access many of these sources through the Internet.
1985;48:15-34. Tukey J. Conclusions vs decisions. Technometrics. 1960; 2(4):423-433. Good IJ. On the principle of total evidence. Br J Philos Sci. 1967;17(4):319-321. 6. Wittgenstein L. Tractatus Logico-Philosophicus. London, England: Routledge Classic; 1922. indd 18 11. Stanovich KE. Rationality and the Reflective Mind. Oxford, UK: Oxford University Press; 2011. 16-10-2014 10:50:47 the foundations 4 What Is the Question? Gordon Guyatt, Maureen O. Meade, Thomas Agoritsas, W. indd 19 17-10-2014 16:46:38 20 The Foundations Three Ways to Use the Medical Literature Consider a medical student, early in her training, seeing a patient with newly diagnosed type 2 diabetes mellitus.
Most experts, however, were recommending therapy despite RCT evidence. Also, as in Figure 2-1, there was a lot of disagreement among experts. 2 Rational clinical decisions require systematic summaries of the best available evidence. Without such summaries, clinicians—expert or otherwise— will be unduly influenced by their own preconceptions and by unrepresentative and often lower-quality evidence. ” Guides to Confidence in Estimates Summaries of the best evidence for diagnosis, prognosis, or treatment present evidence, respectively, for how to interpret test results, predict patients’ likely fate, or understand the impact of alternative management strategies.